PCOS
Essetial oil as a hormone balancer.31 October, 2015
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Wester Red Cedar oil may be effective hormone therapy for UnCommon Women with PCOS!

Essential oils are gaining a reputation for effectiveness that we should pay attention to. Here is a very interesting study of one of my favorite plant medicines, Western Red Cedar, or Thuja occidentals. This is a study using rats and not humans so that is always important to keep in mind when considering result. For instance, the abstract, which is all the info I have available, says that the essential oil was "administered", but it doesn't say how. It's not yet clear how to translate this study into something usable and effective as treatment for you. But a very exciting development none the less!

J Ethnopharmacol. 2015 Jun 20;168:25-30. doi: 10.1016/j.jep.2015.03.029. Epub 2015 Mar 27.

Thuja occidentalis L. and its active compound, α-thujone: Promising effects in the treatment of polycystic ovary syndrome without inducing osteoporosis.

Küpeli Akkol E1İlhan M2Ayşe Demirel M3Keleş H4Tümen I5Süntar İ2.

Author information

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE:

Thuja occidentalis L. (Cupressaceae) has been used in folk medicine for the treatment of rheumatism, amenorrhea, cystitis, and uterine carcinomas, and as an aid to reproduction.

AIM OF THE STUDY:

The present study aimed to determine whether T. occidentalis oil and α-thujone could be beneficial in the treatment of polycystic ovary syndrome (PCOS).

MATERIALS AND METHODS:

T. occidentalis oil and α-thujone were administered to rats with letrozole-induced PCOS for 21 days. At the end of 21 days,  blood samples were taken. The levels of serum gonadotropins, steroids, blood lipid, leptin, and glucose and the values of antioxidant parameters were measured.

RESULTS:

The results demonstrated that estradiol and progesterone levels significantly increased, while luteinizing hormone (LH) and testosterone levels decreased in the T. occidentalis- and α-thujone-administered groups. The plasma low-density lipoprotein-cholesterol (LDL-C), leptin, and glucose concentrations were also significantly decreased in the T. occidentalis and α-thujone groups when compared to the control group. Histopathological findings demonstrated that the T. occidentalis and α-thujone groups displayed good healing. According to the phytochemical analyses, 25 compounds were identified in the T. occidentalis oil. The main constituents of the oil were the monoterpene ketones α- and β-thujone, fenchone, and sabinene, as well as the diterpenes beyerene and rimuene.

CONCLUSION:

T. occidentalis essential oil and its active component, α-thujone, can be used for the treatment of PCOS without inducing osteoporosis.

Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

KEYWORDS:

Cupressaceae; Osteoporosis; PCOS; Thuja occidentalis; α-Thujone

 

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